I am 42, 5'8" @ 180 lbs not in terrible shape, but could be fitter. For about the past week I have had intense aching pain in my left calf, behind my knees and in my lower back. It seems to get worse with rest, not better. I have tried elevating, icing, heat, stretching and nothing helps, it actually seems to aggravate the situation. Ibuprofen relieves it a little, but not entirely. Now the last couple of days I have developed a headache. We were in Mo. recently and got a lot of mosquito bites. I am worried that this could be West Nile, or something else from the mosquito bites.