My wife is being treated for leukemia that was preceded by myelodysplasia. She is at home at this time, waiting for a bone marrow donor. She is experiencing extreme pain in her shoulders, and to a lesser degree, in her knees. She takes Vicodin and Ibuprofen to relieve the pain, but the results are minimal, and she is in a constant state of pain. Other than the use of a heating pad, can you suggest any treatment that might help, even a little? It is so hard to watch her suffer.