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Dr. Andrew Rynne
MD
Dr. Andrew Rynne

Family Physician

Exp 50 years

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What Are The Side Effects Of Epilex Chrono?

Hello sir, I am 26 year old, and I am taking Epilex Chrono 300 and 500 in the morning and in the evening.. I had epilapsy Feat two time in past 7 years and so many time I used to get jerk.If don't take mediceine regularly.I saw so many blogs that this medicine gives side effects to the lever. Is it right? Shall I stop taking that...And if it it is harmfull to lever, then after how long it will affect to lever. Please guide me sir...
Tue, 21 Apr 2015
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Neurologist 's  Response
Hello !
Thank you for the question on HCM! I understand your concern.
Yes it is true, that it can cause liver damage up to liver failure. Liver failure resulting in fatalities has occurred in patients receiving Valproate and its derivatives. These incidents usually have occurred during the first six months of treatment. Signs or liver damage would be non-specific symptoms such as malaise, weakness, lethargy, facial edema, anorexia, and vomiting.
But you have been using this drug for more than 7 years, so things are not very concerning.
I would recommend repeated full blood work and liver function tests every 3-6 months .
If everything is ok, there is nothing to worry about. It is a very effective drug, and I would not recommend to stop it if the tests are ok.
Other side effects beside the liver would be nausea , vomiting , hair loss, weight gain, allergic reactions, gait problems etc. But you have been using it for such a long time, and everything is fine.
Hope to have been of help!
Greetings!
Dr. Abaz Quka
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What Are The Side Effects Of Epilex Chrono?

Hello ! Thank you for the question on HCM! I understand your concern. Yes it is true, that it can cause liver damage up to liver failure. Liver failure resulting in fatalities has occurred in patients receiving Valproate and its derivatives. These incidents usually have occurred during the first six months of treatment. Signs or liver damage would be non-specific symptoms such as malaise, weakness, lethargy, facial edema, anorexia, and vomiting. But you have been using this drug for more than 7 years, so things are not very concerning. I would recommend repeated full blood work and liver function tests every 3-6 months . If everything is ok, there is nothing to worry about. It is a very effective drug, and I would not recommend to stop it if the tests are ok. Other side effects beside the liver would be nausea , vomiting , hair loss, weight gain, allergic reactions, gait problems etc. But you have been using it for such a long time, and everything is fine. Hope to have been of help! Greetings! Dr. Abaz Quka