About halfway up the top of my right thigh, I have occasionally been feeling a pulsating twitch (every 5 or 6 seconds) when sitting or lying in bed. It's not painful, just a bit annoying when I'm aware of it and think about it. I'm guessing it's a pulsating vein, but why is it doing this? Should I be concerned? I am 61, 5 feet 11 1/2 inches tall, weigh 270 pounds, am on medication for type 2 diabetes, cholesterol, and high blood pressure (all of which are in normal limits with the medication) and I work out on the treadmill 2-3 times a week. No major illnesses or physical problems.