3 years ago my mother started to experience confusion especially at night (to the point of falling, being disoriented etc) she got the OK to decrease dose of metropolo from 50 mg per day to 25 mg per day and tolerated that dose well. She recently underwent spinal surgery and had an episode of Afib, metropolol was increased to 50 mg 2x per day (we were not aware of this). She was confused, fatigued and depressed appearing for several weeks following surgery, recently admitted with Pneumonia and a UTI and dose was increased to 75 mg 2x per day. She is now very confused, hallucinating, agitated, and disoriented. No one will listen to me, Doctors claim it is sundowning. My mom is 80 and was living independently prior to her surgery.