5 days ago I had a cortisone shot into my shoulder for arthritis. the pain was intense all weekend and I took 800mg ibuprofen sat. and sun. I am also on 3 prescribed meds full time. 1 Tamsulosin/0.4mg 2. Cartia/120mg and 3. Losartan/12.5mg. all 1/day. today I broke out in a fairly bad case of hives. the shoulder pain is subsiding, so I am assuming the cortisone is kicking in. can the combo of all of the above be causing the hives.