After a colitis flare up 2 wks ago which included knee joint and leg pain, the passing of mucus and blood, bloating & cramping all symptoms subsided after a 7 day period except the knee pain. I've tried Ibuprophen, applying heat, elevating my legs and hot tub soaks to no avail. Very uncomfortable. Knee pain accompanies my flare ups in every instance but always goes away as the other symptoms in a weeks time. Dehydration and getting away from a proper diet bring on the flare ups. I take Asacol 800mg daily. I've had colonoscopies every 5yrs and now have 'graduated' to only having them every 10yrs. I'm female, 69ys of age.