Hi, I have had a thyroid problem for just over a year now (Hypo) I am on 50mg once daily, I also take 20mg of fluoxetine daily. I have been taking my thyroxine in the morning and my fluoxetine at night, I have been struggling with this for a while so starting tonight I have swapped my medication to thyroxine at night and fluoxetine in the morning. I am seeing my GP on Thursday re: blood results which had been taken 2 weeks ago, don't know the results all I have been told is to repeat in 4 to 6 weeks and will discuss results when I see him on Thursday. I also have CKD stage 3 and getting worried about it all, am I doing the right thing changing my meds around. My mood is low and I tire very easy I do have to work my age is 53yrs old.