I have, for two years and since starting a combination of amolidepene and irbestatan, have had often daily, severe and often long-lasting right-side head pain which stretches from the back of my head around my eye, down my jaw and onto my right shoulder. I have seen a pain specialist (take amitripilene);a vascular surgeon, rheumetologist, orthopedic surgeon, dental surgeon, and a neurologist. My personal General Medicine doctor - who recommended all the foregoing specialists and the combo of amolidepene and irbestatan. None of the specialists, oh I forgot the hematologist, found any problems. Is it possible the combo is causing the head pains? My BP often, with the meds, runs about 100/74 or lower.