I Have Tried Quindine, Gabapentin, Lyrica, Etc. With No Discernible

I have tried quindine, gabapentin, lyrica, etc. with no discernible results. I have leg - thigh, calf, ankle, toe - you name it, several times a month. It doesn't seem related to potassium (take 1/2-1 banana/day), amount of water taken. They mainly occur during the night, but I can also get them swimming, especially when bending the knee.