I take 150 mg of sertraline, 40 mg of atorvastatin, 10 mg of zetia, 25 mg of hctz and 2 tablespoons twice a day of lactulose for severe constipation. I am going on a plane and am very fearful. I take the sertraline for depression and OCD. Can I take 5 mg of diazepam before going on the plane and also for coming home with these medications? One is a morning flight which is when I take the sertraline and hctz. The flight coming home is in the evening when I take the atorvastatin, zetia and lactulose. Would this be safe, or is there another medication or over the counter medication that would be better? And can I take the diazepam or other medication at the same time as my regular medication?