I was taking 150 mg of Seroquel in the evening, 1 mg of haloperidol in the AM and PM, and 15 mg of buspirone in the AM and PM for the past few weeks. Previously it was just the Seroquel in combination with some other prescribed drugs (i.e. Wellburtrin and Risperadal) that were not effective. The Seroquel and haloperidol seemed to combat my depression but the the addition of buspirone reversed my progress. Additionally, adding just the haloperidol didn't seem to do anything except provoke more sleeplessness, dry mouth and then weight gain. I went cold turkey on all three drug about ten days ago and I feel awful although I'm sleeping somewhat better and shedding some weight. Suicidal thoughts, however, are increasing.