My brother has had right shoulder pain for three months. It has recently gotten worse in the last couple of weeks. It's worst when moving his arm backwards. Just yesterday he told me he has also had this funny feeling in his chest when he lays down, like there is something in there he needs to cough out. He coughs a couple times, and it goes away for a bit, only to come right back. He's had this for the past few days. Starting yesterday, he noticed some swelling in his ankles, I'd say 2-3+ pitting edema, with the right ankle being worse than the left. I'm pretty worried about him. He has a hx of panic disorder and takes quite a few medications from that, and is a smoker.