My partner was 65 when he developed throat cancer. He had his voice box operated on and they removed the cells and he now has a weak voice, but a voice... He had radiation but not chemo. That was 5 years ago. Particularly in the last 2 years, his behaviour has altered, he fumbles, shuffles, forgets things, drops things, constantly mistakes requests and cant seem to do the simple things he has always done as a matter of course. He even looks older and seems to be getting more house bound etc.