hi , ive been experiencing numbness and tingling in my hand and headaches and my hands and feet seem cold, I seem cold all the time anymore ..also my left foot ,my big toe has 3 dark spots on it that it never had before and I have bad swelling in my legs, like when I take my socks off you can see exactly where my socks stopped on my leg theres a big ring around my leg , a indentation, like pitting edema. what could be going on? I am on topiramate for migraines which when I first started it , it made my hands tingle but I ve been on it for over a year now.. is all this cause for concern?