What Causes Swelling All Over The Body?

I'm a 52 year old woman, I'm 5 foot 4 inches tall, I weigh around 190, I've had ulcer tna, two heart caths, bipass, and an icd put in. Lately I've had swelling every where ,bones hurting from head to toe, loss of appetite,and tired all the time cant get any sleep. What can this be?