Yes, I started with a UTI in January, and was in Cipro first, and then Macrobid because it didn't go away. Came back again in February, and my culture showed greater than 100,000 ml of E-coli. Was good for awhile and then a couple weeks ago it started coming back again. Same thing burning, blood in urine, frequent bathroom. Only this time I hit really back low back pain, pelvis pain and sharp pains in my right side. Got very sick,nauseous, couldn't eat, not like usual. Went to Dr and they said probably UTI again and put me on Cipro, didn't help, so checked for kidney stones and appendix. Both were negative, but my culture said traces of leukocyte, RBC 3-5, and wbc 0-2. Did find a cyst on my kidney, but didn't seem too concerned. I'm so over this, do you have any suggestions Please!!!!