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Are Diminutive Polyps Genetic Due To A Family History Of Colon Cancers?

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Posted on Fri, 22 Dec 2023
Question: my Age is 35 / male

History
Taking pan d for the past 4 months
For reflux related issues
Last week had gastritis symptoms which was not responding to PPI
So doctor adviced for endoscopy

Finding
Diminutive polyp
H pylori negative

Family history
Grandfather died due to colon cancer age 75

My question
Can this polyp is related to genetic
Really scared after checking it on internet like FAP
Tissue sample sent for biopsy
But any idea what this can be
doctor
Answered by Dr. T Chandrakant (1 hour later)
Brief Answer:

As detailed below.

Detailed Answer:

Hi,

Grossly the diminutive polyp cannot be reliably distinguished from a hyperplastic pseudopolyp vs. a small true polyp (adenoma), and hence all such lesions are removed for microscopic analysis.

So the diminutive polyp in your case may be a hyperplastic small lesion.

If the lesion is single then this may not be related to genetics.
FAP have a typical appearance, hence should have been mentioned if present by your Endoscopist.

So stop worrying till the biopsy report is available.
Avoid the stress and anxiety as these can be one of the reasons for gastritis and reflux not responding to PPI.

Hope I have answered your query. Let me know if I can assist you further.
Above answer was peer-reviewed by : Dr. Vaishalee Punj
doctor
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Follow up: Dr. T Chandrakant (16 hours later)
Thankyou for your reply
I have sent pictures of my endoscopic result
Please send me ur comments
doctor
Answered by Dr. T Chandrakant (2 hours later)
Brief Answer:

Please post reports of biopsy

Detailed Answer:

Hello,

Polyps look small without much signs of any dangerous problems.
Well, it is always the histopathology report that clears the doubts. Awaiting the reports.

Hope I have answered your query.

Take care

Regards,
Dr T Chandrakant, General Surgeon
Note: Revert back with your health reports to get further guidance on your gastric problems. Click here.
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
Answered by
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Dr. T Chandrakant

General Surgeon

Practicing since :1984

Answered : 19777 Questions

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Are Diminutive Polyps Genetic Due To A Family History Of Colon Cancers?

Brief Answer: As detailed below. Detailed Answer: Hi, Grossly the diminutive polyp cannot be reliably distinguished from a hyperplastic pseudopolyp vs. a small true polyp (adenoma), and hence all such lesions are removed for microscopic analysis. So the diminutive polyp in your case may be a hyperplastic small lesion. If the lesion is single then this may not be related to genetics. FAP have a typical appearance, hence should have been mentioned if present by your Endoscopist. So stop worrying till the biopsy report is available. Avoid the stress and anxiety as these can be one of the reasons for gastritis and reflux not responding to PPI. Hope I have answered your query. Let me know if I can assist you further.