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Are Lucent Lesions On The Bone Indicative Of Multiple Myeloma?

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Posted on Fri, 19 May 2017
Question: I was referred to a hematologist after my MRI showed small osseous lucenies, so multiple myeloma can't be excluded. (This was a followup to a CT scan for diviticulitis.). Does this mean that I most likely have multiple myeloma?
doctor
Answered by Dr. Deepak Sundriyal (28 minutes later)
Brief Answer:
hello dear. No it doesnot mean myeloma

Detailed Answer:
Hello dear. I have gone through the details. So just having osseous lucencies does not mean you have myeloma. For a diagnosis of myeloma you must have some more test and fullfill the criteria for active disease. You require following tests
Serum protein electrophoresis
Serum calcium
liver function tests including serum proteins
free light chain assay
Please revert back with these reports
Thanks and regards

Above answer was peer-reviewed by : Dr. Kampana
doctor
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Follow up: Dr. Deepak Sundriyal (2 hours later)
I cannot see a hematologist until XXXXXXX 6. Should I have multiple myeloma, can I wait that long?

My reg doctor ordered a Electrophreiss Protein blood test - all of which were within normal levels.
doctor
Answered by Dr. Deepak Sundriyal (1 hour later)
Brief Answer:
I don't think it will be myeloma

Detailed Answer:
Hello dear.

There is no urgency and you can wait. It doesn't look like myeloma.


Thanks and regards


Above answer was peer-reviewed by : Dr. Arnab Banerjee
doctor
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Follow up: Dr. Deepak Sundriyal (22 minutes later)
Will the Hematologist likely to do a biopsy to determine myeloma - or not?
doctor
Answered by Dr. Deepak Sundriyal (4 hours later)
Brief Answer:
If all other tests are negative, it may be done

Detailed Answer:
Hello dear.

If all other tests are negative, it may be done if he thinks there is a high chance of myeloma.

Thanks and regards


Above answer was peer-reviewed by : Dr. Arnab Banerjee
doctor
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Follow up: Dr. Deepak Sundriyal (44 minutes later)
I'm confused. Why would a Hemotologist do a biopsy if all tests are negative? Why do the other tests? Why would the Hemotologist think that it it myeloma is all tests are negative???

Why dont you think that i have myeloma?
doctor
Answered by Dr. Deepak Sundriyal (11 minutes later)
Brief Answer:
It depends upon the lesion

Detailed Answer:
Hello dear.

There is an entity called plasmacytoma in which all other tests are negative. It can be picked only by biopsy of the lesion. Or sometimes there is non-secretory myeloma in which only marrow is positive.

Then a marrow biopsy is indicated. It's complex for you but only the physician who is closely examining you can decide exactly.

Still, in my opinion, I'd again say, it doesn't look like myeloma. But tests need to be done to rule out that.

Thanks and regards

Brief Answer:
Hello. As you do not have any symptoms.

Detailed Answer:
Hello dear. Its because you do not have any symptom of bony pains, any fracture, no history of repeated infections, protein electrophoresis is normal and merely bony lucencies which can be anything else too.
Hence i donot think you have myeloma.
Thanks and regards
Note: Do you have more questions on diagnosis or treatment of blood disorders? Ask An Expert/ Specialist Now

Above answer was peer-reviewed by : Dr. Arnab Banerjee
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Answered by
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Dr. Deepak Sundriyal

Oncologist

Practicing since :2005

Answered : 1655 Questions

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Are Lucent Lesions On The Bone Indicative Of Multiple Myeloma?

Brief Answer: hello dear. No it doesnot mean myeloma Detailed Answer: Hello dear. I have gone through the details. So just having osseous lucencies does not mean you have myeloma. For a diagnosis of myeloma you must have some more test and fullfill the criteria for active disease. You require following tests Serum protein electrophoresis Serum calcium liver function tests including serum proteins free light chain assay Please revert back with these reports Thanks and regards