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Are People Of Certain Blood Groups More Prone To Particular Diseases?
Question: Are people of certain blood groups more prone to particular diseases?
Brief Answer:
Yes researches have shown such associations
Detailed Answer:
Hi XXXX
Thanks for writing in to us.
I have read through your query in details.
The point raised by you is very interesting and debatable at the same time. Multiple researches have been done over the last half century on the same topic and many new conclusions have been reached with advances in medicine.
In the last few years a research team from UK has found that blood group AB is associated with increased risk for severe dengue disease in secondary infections. Malaria has been found to be associated with certain genes coding for blood groups too.
Another research in XXXXXXX shows that in cancer patients, the incidence of A group was higher in breast, lung, kidney and bladder cancers, though when all cancers were taken together, the incidence of B blood group was highest, followed by A group.
Stomach problems and gastritis is more common in blood group A individuals.
So you see that there are many researches which have found particular blood groups associated with diseases.
If you are searching for any particular disease in particular then we can discuss that in detail.
Hope your query is answered.
Do write back if you have any further doubts.
Regards,
Dr.Vivek
Yes researches have shown such associations
Detailed Answer:
Hi XXXX
Thanks for writing in to us.
I have read through your query in details.
The point raised by you is very interesting and debatable at the same time. Multiple researches have been done over the last half century on the same topic and many new conclusions have been reached with advances in medicine.
In the last few years a research team from UK has found that blood group AB is associated with increased risk for severe dengue disease in secondary infections. Malaria has been found to be associated with certain genes coding for blood groups too.
Another research in XXXXXXX shows that in cancer patients, the incidence of A group was higher in breast, lung, kidney and bladder cancers, though when all cancers were taken together, the incidence of B blood group was highest, followed by A group.
Stomach problems and gastritis is more common in blood group A individuals.
So you see that there are many researches which have found particular blood groups associated with diseases.
If you are searching for any particular disease in particular then we can discuss that in detail.
Hope your query is answered.
Do write back if you have any further doubts.
Regards,
Dr.Vivek
Above answer was peer-reviewed by :
Dr. Chakravarthy Mazumdar
My family has a history of heavy drinking. My son has just died from alcoholic liver disease, aged 44. I am 69 and well. My daughter aged 48 drinks too yet her liver tests have come back perfect like that of a non-drinker. My blood group is O positive. When in hospital, I noticed the blood products given to my late son were Group A and AB. The gastro enterologist treating my son was amazed that he had end stage cirrhosis of the liver, yet had never been ill before. I wondered if the blood type had any bearing on this and could it be the reason why some of live to a great age yet continue to abuse alcohol. Thank you. I look forward to your reply.
XXXX
XXXX
Brief Answer:
Alcoholic liver disease has multifactorial causes
Detailed Answer:
Hi
Thanks for writing back with an update.
Review of medical literature says that the spectrum of Alcoholic Liver Disease includes fatty changes with or without fibrosis in virtually all individuals with an alcohol consumption of >80 g/day, alcoholic fatty hepatitis of variable severity in 10–35% and liver cirrhosis in approximately 15% of patients. Once cirrhosis is established, there is an annual risk for hepatocellular carcinoma (liver cancer) of 1–2%. Environmental factors such as drinking patterns, coexisting liver disease, obesity, diet composition and medication may modify the natural course of Alcoholic Liver Disease.
Concerning your particular query about blood groups and liver disease, cancers of the liver show a slight association with blood type A. The predisposition of alcohol liver disease is a cumulative effect of multiple genes, cumulative alcohol intake, nutrition of the individual and environmental conditions and not due to a single factor like blood group or single gene. The progress of cirrhosis to end stage liver disease and liver caner also varies with multiple factors.
Hope your query is answered.
Do write back if you have any further doubts.
Regards,
Dr.Vivek
Alcoholic liver disease has multifactorial causes
Detailed Answer:
Hi
Thanks for writing back with an update.
Review of medical literature says that the spectrum of Alcoholic Liver Disease includes fatty changes with or without fibrosis in virtually all individuals with an alcohol consumption of >80 g/day, alcoholic fatty hepatitis of variable severity in 10–35% and liver cirrhosis in approximately 15% of patients. Once cirrhosis is established, there is an annual risk for hepatocellular carcinoma (liver cancer) of 1–2%. Environmental factors such as drinking patterns, coexisting liver disease, obesity, diet composition and medication may modify the natural course of Alcoholic Liver Disease.
Concerning your particular query about blood groups and liver disease, cancers of the liver show a slight association with blood type A. The predisposition of alcohol liver disease is a cumulative effect of multiple genes, cumulative alcohol intake, nutrition of the individual and environmental conditions and not due to a single factor like blood group or single gene. The progress of cirrhosis to end stage liver disease and liver caner also varies with multiple factors.
Hope your query is answered.
Do write back if you have any further doubts.
Regards,
Dr.Vivek
Note: For detailed guidance on genetic screening consult a genetics specialist
Above answer was peer-reviewed by :
Dr. Chakravarthy Mazumdar
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