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Are Severe Fatigue, Sweating And Hypertension Signs Of Adrenal Tumor?

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Posted on Wed, 23 Mar 2016
Question: My Endocrinologist has tested every hormone in me to see if there is any correlation of the lab results to the symptoms I experience. If All tests come back normal for adrenal gland type of medical issues, can a person have an Adrenal Tumor still or would the lab results be altered if so? Symptoms- Tired, despite CPAP, sweat alot, but really bad lately and not doing much physically; hypertension spiked Very high about 8 months ago;
I have anxiety/dep and an on Zoloft and xanax prn. 5 BP drugs, Insulin for type 2,
Metabolic Syndrome patient
Thank you, XXXXXXX
doctor
Answered by Dr. Binu Parameswaran Pillai (1 hour later)
Brief Answer:
Adrenal symptoms

Detailed Answer:
Good day,
Noted your concern.
Anxiety/depression itself can mimic like adrenal gland disorders ( particularly can mimic like symptoms of Cushing's syndrome and Pheochromocytoma).
It is good to discuss with your doctor if he has ruled out these adrenal disorders and doing appropriate urine and blood test.
If you are using 5 BP medicines, I would strongly search for adrenal dosorders like pheochromocytoma, hyper aldosteronism and Cushing's syndrome.

Not all adrenal tumors may have symptoms. Many a times, adrenal nodules can exist with out any symptoms or abnormalities in blood tests. These are found on scans done for other reasons and these are then called as adrenal incidentaloma.
Regards
Binu

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
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Follow up: Dr. Binu Parameswaran Pillai (5 hours later)
Have had two kidney ultrasounds if those would also pick up adrenal abnormalities.
Attached are many hormone tests over the last year or so. Thanks for your opinion XXXXXXX
doctor
Answered by Dr. Binu Parameswaran Pillai (1 hour later)
Brief Answer:
Abnormal results

Detailed Answer:
Hi,
Thank you for the reply.
I could identify few issues.
A low testosterone ( I don't believe in direct free testosterone assay).
A suppressed Renin and an aldosterone of > 15. And a low cortisol level.
All these need further evaluation.
A suppressed renin with a high Aldosterone to renin ratio is suggestive of Hyper aldosteronism. This could be causing your high blood pressure ( provided they did the test properly). You now need second line tests like saline loading test and may require a CT scan of adrenal. Ultrasound is not good enough to look at adrenal glands.

Cortisol is low too. So you need a Synacthen test and an ACTH level ( 8 AM).
You need to discuss with your endocrinologist seriously.
Note: For more information on hormonal imbalance symptoms or unmanaged diabetes with other comorbid conditions, get back to us & Consult with an Endocrinologist. Click here to book an appointment.

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
Answered by
Dr.
Dr. Binu Parameswaran Pillai

Endocrinologist

Practicing since :2003

Answered : 1438 Questions

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Are Severe Fatigue, Sweating And Hypertension Signs Of Adrenal Tumor?

Brief Answer: Adrenal symptoms Detailed Answer: Good day, Noted your concern. Anxiety/depression itself can mimic like adrenal gland disorders ( particularly can mimic like symptoms of Cushing's syndrome and Pheochromocytoma). It is good to discuss with your doctor if he has ruled out these adrenal disorders and doing appropriate urine and blood test. If you are using 5 BP medicines, I would strongly search for adrenal dosorders like pheochromocytoma, hyper aldosteronism and Cushing's syndrome. Not all adrenal tumors may have symptoms. Many a times, adrenal nodules can exist with out any symptoms or abnormalities in blood tests. These are found on scans done for other reasons and these are then called as adrenal incidentaloma. Regards Binu