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Are Tiredness And Pulmonary Embolism Long Term Side Effects Of Tramadol?

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Posted on Tue, 21 Apr 2015
Question: Hi, can long term (10+ years) of high dose Tramadol (200 - 400 mg per day) contribute to tiredness, sedentary lifestyle & ultimately Pulmonary Embolism?
doctor
Answered by Dr. Prof. Kunal Saha (1 hour later)
Brief Answer:
Are you sure that the pulmonary embolism has no other causes?

Detailed Answer:
Thanks for asking on Health Care Magic.

Tramadol is an opioid analgesic or central nervous system depressant associated with physical dependence and may give rise to drowsiness or sedation. Therefore feeling of tiredness is not unlikely.
About Pulmonary Embolism, I do not find a correlation. It can be a concurrent factor rather than being linked as a cause-effect relationship.

Hope that helps.

Regards
Dr. Kunal Saha
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
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Follow up: Dr. Prof. Kunal Saha (35 minutes later)
Definitely no other causes found. 6 months of sob, then multiple PE both lungs. 10 years prior to the PE he had an operation for acoustic neuroma which went wrong. CSF leaks, pneumonia, Hydrocephalus, meningitis followed, culminating in a shunt mal insertion causing stroke!! Hypersensitivity due to stroke is the reason for the Tramadol. Trying to link something to the PE.

Any suggestions?
doctor
Answered by Dr. Prof. Kunal Saha (20 hours later)
Brief Answer:
The risk factors for pulmonary embolism already seem to be present

Detailed Answer:
Thanks for writing back. Sorry for not being able to respond back earlier.

Let me mention a simple thing. What stroke is for the brain, is same as pulmonary embolism for brain. In either case, a small particulate matter (embolus) gets struck in a small vessel and thereby clogs it and blocks the blood flow to the portions further on route. We have two parallel circulations going on in our body. The right circulation is to the lungs and back; the left circulation is to the different parts of the body and back. So, the person having risk factors for stroke definitely can be susceptible to pulmonary embolism as well.

Moreover, in case of the other associated factors that you have mentioned, it is not unlikely for some small fat globule or something else to get dislodged from somewhere and be responsible for the pulmonary embolism.

I do not link it to tramadol.

Hope that helps.

Regards
Dr. Kunal Saha
Note: For more detailed guidance, please consult an Internal Medicine Specialist, with your latest reports. Click here..

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
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Answered by
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Dr. Prof. Kunal Saha

General & Family Physician

Practicing since :1954

Answered : 4467 Questions

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Are Tiredness And Pulmonary Embolism Long Term Side Effects Of Tramadol?

Brief Answer: Are you sure that the pulmonary embolism has no other causes? Detailed Answer: Thanks for asking on Health Care Magic. Tramadol is an opioid analgesic or central nervous system depressant associated with physical dependence and may give rise to drowsiness or sedation. Therefore feeling of tiredness is not unlikely. About Pulmonary Embolism, I do not find a correlation. It can be a concurrent factor rather than being linked as a cause-effect relationship. Hope that helps. Regards Dr. Kunal Saha