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Are Weight Gain And Swelling At The Ankles Due To High Blood Sugar Levels And What Should Be Done?

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Posted on Fri, 11 Mar 2022
Question: Hi Doctor,
My wife went on insulin approx. 15 days ago, for high blood sugar. Her last several readings have been 130 down to 119. Her ankles are swollen, and she was told by the nurse, at her MD's office to have her GP script a diuretic. She is also puttig on weight!

Thanks
doctor
Answered by Dr. Panagiotis Zografakis (1 hour later)
Brief Answer:
investigation is required

Detailed Answer:

Hello,

I don't believe that insulin treatment has anything to do with her weight gain. Insulin does result in weight gain in many patients but this only occurs because of fat accumulation as more sugar becomes available to the patient's cells. Therefore leg swelling is not expected.

Swelling on the other hand and rapid weight gain is usually associated with fluid overload and/or retention. I can't just guess why she's having fluid retention but the most common causes include heart failure, renal disorders, venous insufficiency, drug side effects, etc. Therefore investigation is required to find the underlying mechanism that caused her legs to accumulate water. If she's already diagnosed with any of the aforementioned disorders then you've probably got your answer. Otherwise testing should be done to confirm - or exclude - them.

Most of these disorders can be
Heart failure can be assessed with a heart echo (an ultrasound scan of the heart). Renal disorders can be detected with simple measurements of blood urea and creatinine, serum albumin and total protein levels and a urinalysis.
Venous insufficiency can be diagnosed with an ultrasound scan of the leg veins (triplex). The side effects cannot be diagnosed directly. Other causes have to be excluded before a drug can be 'accused' of causing a certain side effect.

I hope my comments are helping you to understand her situation better. Please get back to me, if you'd like me to clarify anything or if you need more information.
Regards
Note: For more detailed guidance, please consult an Internal Medicine Specialist, with your latest reports. Click here..

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
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Answered by
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Dr. Panagiotis Zografakis

Internal Medicine Specialist

Practicing since :1999

Answered : 3818 Questions

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Are Weight Gain And Swelling At The Ankles Due To High Blood Sugar Levels And What Should Be Done?

Brief Answer: investigation is required Detailed Answer: Hello, I don't believe that insulin treatment has anything to do with her weight gain. Insulin does result in weight gain in many patients but this only occurs because of fat accumulation as more sugar becomes available to the patient's cells. Therefore leg swelling is not expected. Swelling on the other hand and rapid weight gain is usually associated with fluid overload and/or retention. I can't just guess why she's having fluid retention but the most common causes include heart failure, renal disorders, venous insufficiency, drug side effects, etc. Therefore investigation is required to find the underlying mechanism that caused her legs to accumulate water. If she's already diagnosed with any of the aforementioned disorders then you've probably got your answer. Otherwise testing should be done to confirm - or exclude - them. Most of these disorders can be Heart failure can be assessed with a heart echo (an ultrasound scan of the heart). Renal disorders can be detected with simple measurements of blood urea and creatinine, serum albumin and total protein levels and a urinalysis. Venous insufficiency can be diagnosed with an ultrasound scan of the leg veins (triplex). The side effects cannot be diagnosed directly. Other causes have to be excluded before a drug can be 'accused' of causing a certain side effect. I hope my comments are helping you to understand her situation better. Please get back to me, if you'd like me to clarify anything or if you need more information. Regards