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Can Colchicine Be Taken With Diclofenac For Gout?

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Posted on Wed, 11 Jul 2012
Question: Can i take colchicine and diclofenac/naproxsyn at the same time for gout?

Gout attack in left hand centred at the ring finger base joint to palm.
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Answered by Dr. Sathyadharan Panneer (2 hours later)
Hi,

Thanks for writing in,

For acute gout, the 1st line of drug is NSAID's (diclofenac/naproxen). Because of side effects like abdominal cramps, diarrhea etc., Colchicine is preferred as 2nd line of drug. Combining both the drugs might increase the gastro-intestinal side effects. Otherwise there is not much of drug-to-drug interactions between colchicine /NSAID's. Except for initial few days of acute flare-up of gout the combination is never preferred or needed.

I hope I have addressed your concerns.

Regards.
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Above answer was peer-reviewed by : Dr. Aparna Kohli
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Answered by
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Dr. Sathyadharan Panneer

Orthopaedic Surgeon

Practicing since :2004

Answered : 189 Questions

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Can Colchicine Be Taken With Diclofenac For Gout?

Hi,

Thanks for writing in,

For acute gout, the 1st line of drug is NSAID's (diclofenac/naproxen). Because of side effects like abdominal cramps, diarrhea etc., Colchicine is preferred as 2nd line of drug. Combining both the drugs might increase the gastro-intestinal side effects. Otherwise there is not much of drug-to-drug interactions between colchicine /NSAID's. Except for initial few days of acute flare-up of gout the combination is never preferred or needed.

I hope I have addressed your concerns.

Regards.