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Can Diphenhydramine Cause A False Positive Urine Test?

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Posted on Thu, 2 Apr 2015
Question: Can diphenhydramine cause a false positive on a urine test ? If yes, what can it show up as ?
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Answered by Dr. Rahul Tawde (30 minutes later)
Brief Answer:
Yes, can cause false positive urine test on following drugs...

Detailed Answer:
Hi,

Diphenhydramine can cross-act with immunoassays and cause a false positive on a urine test to:
- methadone
- Phencyclidine
- opiates
- Tricyclic ntidepressants

Hope it answered to your queries! Let me know if I can assist you further!
Dr.Sejdini
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
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Answered by
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Dr. Rahul Tawde

General & Family Physician

Practicing since :1980

Answered : 1 Question

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Can Diphenhydramine Cause A False Positive Urine Test?

Brief Answer: Yes, can cause false positive urine test on following drugs... Detailed Answer: Hi, Diphenhydramine can cross-act with immunoassays and cause a false positive on a urine test to: - methadone - Phencyclidine - opiates - Tricyclic ntidepressants Hope it answered to your queries! Let me know if I can assist you further! Dr.Sejdini