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Can Flecainide And Prograf Be Taken Together?

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Posted on Fri, 12 May 2023
Question: I had a liver and kidney transpkant in 4/10/2010. Recently, they found out I had A fib. They did the usual check for blood clots and shocked my heart to put it back nto the proper beats. The doctor prescribed flecainide 50 mg 2x daily. My question is my transplant twam seems worried about this. Is there a problem between the Prograf (Tacrolimus) 4 mg per day and the flecanide??
doctor
Answered by Dr. salah saad shoman (6 minutes later)
Brief Answer:

Moderate interaction

Detailed Answer:

Hello,

Unfortunately, both medications can interact if taken together as using flecainide together with Tacrolimus can increase the risk of an irregular heart rhythm that may be serious and potentially life-threatening.

Although it is a relatively rare side effect you may be more susceptible since you have a heart condition in the first place.

Hope I have answered your query. Let me know if I can assist you further.

Take care

Regards,
Dr Salah Saad Shoman, Internal Medicine Specialist
Above answer was peer-reviewed by : Dr. Arnab Banerjee
doctor
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Follow up: Dr. salah saad shoman (48 minutes later)
I'm unable to get ahold of my cardiologist, so should I quit taking the flecainide until I am able to get ahold of him?? Or instead of taking 2x a day should I take it once a day, or stop taking it until I see my cardiologist?? Right now I am taking 50mg 2x a day. Thank you for your insight.
doctor
Answered by Dr. salah saad shoman (11 minutes later)
Brief Answer:

Cutting off the dose must be done under medical supervision

Detailed Answer:

Hello,

Discontinuing Flecainide should always be done under the strict medical supervision and it should be substituted by another agent to control atrial fibrillation such as beta blockers.

We're discussing potentially serious side-effects hence it's not at all recommended to do this on your own.

In the meanwhile please monitor yourself for any irregular heartbeats, dizziness or fainting. If at all observed then seek medical attention (to the nearest Urgent care/ER) as soon as possible.

Hope I have answered your query.

Take care

Regards,
Dr Salah Saad Shoman, Internal Medicine Specialist
Note: For more detailed guidance, please consult an Internal Medicine Specialist, with your latest reports. Click here..

Above answer was peer-reviewed by : Dr. Arnab Banerjee
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Answered by
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Dr. salah saad shoman

Internal Medicine Specialist

Practicing since :2004

Answered : 3151 Questions

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Can Flecainide And Prograf Be Taken Together?

Brief Answer: Moderate interaction Detailed Answer: Hello, Unfortunately, both medications can interact if taken together as using flecainide together with Tacrolimus can increase the risk of an irregular heart rhythm that may be serious and potentially life-threatening. Although it is a relatively rare side effect you may be more susceptible since you have a heart condition in the first place. Hope I have answered your query. Let me know if I can assist you further. Take care Regards, Dr Salah Saad Shoman, Internal Medicine Specialist