Brief Answer: Yes this drugs can be interchanged. Detailed Answer: Hello! I am Dr.Rovena I had gone through your query and medical history. Fluvoxamine and Fluoxetine are members of the same class of drugs called selective serotonin reuptake inhibitors (SSRIs). Both of them are used to treat some disorders such as Major depression,Obsessive-compulsive disorder.They have similar efficacy and safety profiles in the treatment of major depressive episode I don't know the reason why you want to switch them but very studies are made to compare this two drugs and their results indicate that both drugs were well tolerated and there were no marked differences in their side effect profiles which were typical of SSRIs. The findings of this study indicate that fluvoxamine may have a faster onset of action with respect to resolution of depressive symptoms and result in a better improvement in sleep quality. Fluvoxamine and Fluoxetine were equally effective in reducing depressive symptoms, but the two drugs displayed slightly different side-effect profiles. So to answer your question Yes these drugs can be interchanged. But just to be prudential I suggest to consult your treating doctor before you do any changes in your treatment and he will advise you If you should change it and how to use the new drug. Hope I was able to help you.If you have any further question I will be happy to help. Take care. Dr.Rovena

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