Brief Answer: Yes Detailed Answer: Hi and thank you so much for this query. I have taken a look at your medications. Taking luvox and klonopin may increase the effects of klonopin. This can lead to excessive drowsiness, confusion, muscle weakness, etc. If this was prescribed by your doctor, then please you can continue to take the drugs while paying attention to some of the exaggerated effects of klonopin cited above. Pepcid would in no way affect or interact with either of the above medications and it is safe to use them together. I hope this answers your query fully. I wish you well. Feel free to ask for clarifications if need be. Thanks. Dr. Ditah, MD

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