Can Oxycodone,Nabumetone,Ibuprofen And Cyclobenzaprine Be Taken Together?

Posted on Thu, 17 Apr 2014

Medically reviewed by Ask A Doctor - 24x7 Medical Review Team

Thu, 17 Apr 2014 Answered on

Wed, 14 May 2014 Last reviewed on

Question : i took oxycodone, nabumetone, ibuprofen, and cyclobenzaprine, is that bad?

Answered by Dr. Praveen (2 hours later)

Brief Answer:
Potassium and coagulation need close monitoring

Detailed Answer:
Hi.Thanks for giving me an opportunity for answering your query.

I were to closely monitor both coagulation parameters(by doing PT/APTT) and serum potassium levels because of the interactions of the drugs which I have mentioned below.

buprofen + nabumetone
Both increase anticoagulation(chance of bleeding).

ibuprofen + nabumetone
Both increase serum potassium.

cyclobenzaprine + oxycodone
cyclobenzaprine and oxycodone both increase sedation.

Hope this answers your query.

Above answer was peer-reviewed by : Dr. Shanthi.E