Brief Answer: Not to be taken together for 2 reasons Detailed Answer: Thank you for asking! Phosphatidylserine is a neuropsychiatric herbal remedy for cognitive impairment, dementia and ADHD and Depression and it loses its effectiveness with extended use > 16 weeks. Now your query of using them together is whether safe or not? The answer to which is No because of two reasons. 1) Phosphatidylserine though new drug has not been reported with its detailed adverse effects policy and contraindications yet, but its mechanism counteracts the mechanism of trihexyphenidyl that is former is procholinergic and later is anticholinergic , so both nullify the effects here. 2)Abilify and klonopin are not to be used together as they both do the same job and boost each other responses by increased sedation and needs a constant close monitoring and should not be taken together. So a herbal neuropsychiatric Phosphatidylserine, An Antipsychotics & 2nd Generation Antimanic Agent Abilify, An Antiparkinson & Anticholinergics trihexyphenidyl and An Anticonvulsants & Antianxiety & Anxiolytics Benzodiazepine of Klonopin / clonazepam are not to be taken together and a psychiatrist to be consulted for this and a rescheduling of doses and medicines after a complete clinical correlation with ultimate decision which will be in favour of you. Thats the best i can do from thousands of mile with only power over my key board to deliver what is best for you. I hope it help. Dont forget to close the discussion please.May the odds be ever in your favour. S Khan

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Brief Answer: Books follow patients, Patients don't follow books Detailed Answer: thank you for getting back to me! As i mentioned the two medicines abilify and klonopin are pharmacodynamic synergist of each other or in simple words they boost each other effects and thus needs to be closely monitored and better to be avoided. Its working like charm for you is a good thing and boost for this geriatric age explains that. Better seek a psychiatrist opinion and let him decide what is best. As far as i am concerned i mentioned pure literature from reports and feedback of the patients. And patients response may vary from one patient to another as it is said highlighted in our profession that books follow patients and patients don't follow books. And phosphatidyl serine mentioning was because of the mechanism of action and one being procholinergic and other being anticholinergic is again all literature as PS has not yet enough statistics. Well shakspeer said All is well that ends well. So good for you.Seek a psychiatrist opinion for further management. i am sorry for the inconvenience but all my data was from the core of the medical literature and statistics. Take care and good luck.

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Brief Answer: Thank You Detailed Answer: Thank you for being so candid listener. I appreciate it. I am happy to help. Let me know if there is some thing else i can do for you. Dont forget to close the discussion please. Regards

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