Can Synarel Reduce Testosterone Production?

Posted on Thu, 6 Jul 2017

Question: Can a male take synarel nasal spray or nafarelin spray to reduce testosterone. Is the effect same as lupron or eligard? Thanks. Male. 34

Answered by Dr. Mirjeta Guni (32 minutes later)

Brief Answer:
Testosterone lowering therapy:

Detailed Answer:
Hello and thank you for asking!
Synarel has antiestrogenic effects while Nafarelin together with lupron or eligard are gonadotropine analogues. Antiandrogenics are also efficient in lowering the testosterone levels.
I would suggest antiandrogenics as the first line of treatment than gonadotropine analogues (nafarelin spry), or lupron with the same effect.
Hope the information will help.
Kind regards,
Dr.Mirjeta

Above answer was peer-reviewed by : Dr. Vaishalee Punj

Follow up: Dr. Mirjeta Guni (4 hours later)

I m on cyproterone acetate 100mg daily since last 2 years so does that mean I m infertile based on what the research says? I don't want to do any semen analysis.

Answered by Dr. Mirjeta Guni (27 minutes later)

Brief Answer:
About antiandrogenic therapy side effects:

Detailed Answer:
Hello,

Although researchers say that it may cause infertility, it does not mean that every person will have this side effect.

About remaining fertile, you should be under strict monitoring and supervision of your doctor!

Regards,
Dr.Mirjeta

Above answer was peer-reviewed by : Dr. Arnab Banerjee

Follow up: Dr. Mirjeta Guni (5 hours later)

But the chances are high that I m infertile? I don't mind that actually.

Answered by Dr. Mirjeta Guni (25 hours later)

Brief Answer:
The chances are not high:

Detailed Answer:
Hello,
The chances are not high, but exists the possibility.
Regards,
Dr.Mirjeta

Above answer was peer-reviewed by : Dr. Yogesh D

Follow up: Dr. Mirjeta Guni (1 hour later)

How to make the chances high? Do you recommend any other medications or a combination? Thanks

Answered by Dr. Mirjeta Guni (17 hours later)

Brief Answer:
infertility in men;

Detailed Answer:
Hi again,

5 alpha-reductase inhibitors (finasteride, dutaseride, and propecia): are used to treat prostate enlargement and hair loss.

The impact of these medications in infertility is mild and may reverse once the medication is stopped. Men can have a decrease in the volume of the semen, and the total number of sperm in the semen, which may make it harder to cause a pregnancy.

Up to 5% of men taking this medication for either reason can have a major reduction in their sperm numbers.

It causes also tenderness and swelling of the breast and low libido.
Other medications have very low chances to cause infertility.

Best wishes,
Dr.Mirjeta

Note: For more information on hormonal imbalance symptoms or unmanaged diabetes with other comorbid conditions, get back to us & Consult with an Endocrinologist. Click here to book an appointment.

Above answer was peer-reviewed by : Dr. Arnab Banerjee