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Can Amoxicillin 500 Mg Cause Intermittent Loose Stool / Diarehea?

Posted on Wed, 17 Apr 2024

Question: I am a 47 year old female. I have just completed a five day course of amoxicillin 500 mg three times a day. Five days after last dose (yesterday) I began experiencing intermittent loose stool/diarehea. Could this be related to amoxicillin. I am concerned about c-diff. My question how can I tell the difference between a standard reactio to antibiotics which will clear with time and something more serious such as c-diff. The loose stools are intermittent and this morning my first movement of two was fully formed the second a bit looser.

Answered by Dr. Ramesh Kumar (21 hours later)

Brief Answer:
Please go through detailed answer.

Detailed Answer:
Hi,
Amoxicillin most common side effect is loose motions.
To rule out clostridium diff infection you can go for a stool routine test with culture of stools

Start taking any probiotic like VSl #3 two times a day to replenish the good bacteria of gut which are destroyed by Amoxicillin.
Thank you

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar

Follow up: Dr. Ramesh Kumar (35 minutes later)

Thanks for your reply. How long does it typically take for your gut to recover after a round of antibiotics? My stools were a bit firmer this morning. If I was to be infected with c-diff am I to assume that the diarehea would get progressively worse before treatment and not firm stool formation?

Answered by Dr. Ramesh Kumar (55 minutes later)

Brief Answer:
Follow up.

Detailed Answer:
Hi ,
I would suggest you to take probiotic for 5 days initially with soft diet and yoghurt.
After that if things don't improve we would move for stool culture etc.
Thanks

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Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar