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Can One Have 100mg Zoloft Instead Of 20mg Paxil?

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Posted on Mon, 21 Dec 2015
Question: I have been on 20 mg of Paxil for years. Now my Dr. has prescribed 100mg Zoloft with no tapering. What would you advise?


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Answered by Dr. Sassen S Kwasa (1 hour later)
Brief Answer:
I would bring upo your concerns with your doctor...

Detailed Answer:
Welcome to HCM: Please note that you should have a say in the care of your medical conditions and really if you feel uncomfortable with a plan discuss it, bring it up, otherwise we are not doing you justice, please let him know that you will feel more comfortable to taper the medications and he should provide you a plan to do the same and appropriate followup and planing. in any event, what I would do is start taking 10mg daily for 2 weeks, then 10 mg every other day for 2 weeks then 7.5mg or 5mg every other day for 2 weeks. Please note that if what you have are extended release tablets, then these should not be cut, you will need to get the correct strengths from the chemist. I hope this helps
Above answer was peer-reviewed by : Dr. Yogesh D
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Follow up: Dr. Sassen S Kwasa (1 hour later)
Should I take the new prescription ......Zoloft at the same time?
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Answered by Dr. Sassen S Kwasa (58 minutes later)
Brief Answer:
Yes you would take the new one at the same time, the reason being...

Detailed Answer:
antidepressants take a little while to work, and therefore it will make sense for you to have something in the system before the new one kicks in so to speak. Many would says that you should start feeling effect in 2 weeks with peak efficacy around 6-8 weeks after starting the drug.
Note: For further follow up on related General & Family Physician Click here.

Above answer was peer-reviewed by : Dr. Yogesh D
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Answered by
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Dr. Sassen S Kwasa

Internal Medicine Specialist

Practicing since :2012

Answered : 502 Questions

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Can One Have 100mg Zoloft Instead Of 20mg Paxil?

Brief Answer: I would bring upo your concerns with your doctor... Detailed Answer: Welcome to HCM: Please note that you should have a say in the care of your medical conditions and really if you feel uncomfortable with a plan discuss it, bring it up, otherwise we are not doing you justice, please let him know that you will feel more comfortable to taper the medications and he should provide you a plan to do the same and appropriate followup and planing. in any event, what I would do is start taking 10mg daily for 2 weeks, then 10 mg every other day for 2 weeks then 7.5mg or 5mg every other day for 2 weeks. Please note that if what you have are extended release tablets, then these should not be cut, you will need to get the correct strengths from the chemist. I hope this helps