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Can Severe Prolonged Stress Cause Peptic Ulcer In Stomach?

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Posted on Sat, 8 Feb 2014
Question: Hi my name is Kim, and I was wondering is you could get and ulcer from having so much stress in your life?
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Answered by Dr. Ashish Verma (33 minutes later)
Brief Answer: yes surely it can Detailed Answer: Hi XXXXXXX Thanks for writing to XXXXXXX This is Dr. Ashish Verma, a general surgeon, answering to your query. Yes severe prolonged stress is known to cause peptic ulcer in stomach, and this has been conclusively proven in various studies. The major effects of stress on gut physiology include: 1) alterations in gastrointestinal motility; 2) increase in visceral perception; 3) changes in gastrointestinal secretion; 4) increase in intestinal permeability; 5) negative effects on regenerative capacity of gastrointestinal mucosa and mucosal blood flow; and 6) negative effects on intestinal microbial flora. Hope i have answered all your queries. If you have further queries, i will be glad to answer them. Regards Dr. Ashish Verma
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Above answer was peer-reviewed by : Dr. Vaishalee Punj
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Dr. Ashish Verma

General Surgeon

Practicing since :2008

Answered : 1290 Questions

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Can Severe Prolonged Stress Cause Peptic Ulcer In Stomach?

Brief Answer: yes surely it can Detailed Answer: Hi XXXXXXX Thanks for writing to XXXXXXX This is Dr. Ashish Verma, a general surgeon, answering to your query. Yes severe prolonged stress is known to cause peptic ulcer in stomach, and this has been conclusively proven in various studies. The major effects of stress on gut physiology include: 1) alterations in gastrointestinal motility; 2) increase in visceral perception; 3) changes in gastrointestinal secretion; 4) increase in intestinal permeability; 5) negative effects on regenerative capacity of gastrointestinal mucosa and mucosal blood flow; and 6) negative effects on intestinal microbial flora. Hope i have answered all your queries. If you have further queries, i will be glad to answer them. Regards Dr. Ashish Verma