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Can The Intake Of Ziprasidone, Olanzapine And Clomipramine Cause Liver Damage?

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Posted on Mon, 5 Dec 2016
Question: Can these kinds of meds like Ziprasidone, Olanzapine, and Clomramine harm the liver? Please let me know.

Should the doctor check my blood every month?
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Answered by Dr. Dholariya Sagar Jayantilal (5 hours later)
Brief Answer:
Can cause mild hepatic damage

Detailed Answer:
Hello dear
Welcome to HCM and thanks for the query
I understand your concern

Ziprasidone, Olanzapine, and Clomramine can harm the liver on long time use.
But liver damage will not occur in all cases.
Chance of liver damage is high if you have already any liver disease.
All these drugs can cause mild to moderate elevation of liver enzymes, mild hepatitis.
All these side effects are usually mild, asymptomatic and transient, reversing even with continuation of medication.
Severe side effects are rare and if occurs it will rapidly disappear after discontinuation of the drugs.
You should repeat the liver profile every 6-8 months.
So do not worry and take drugs under the advise of your psychiatric.

Hope I have answered your query
If you have further query then I will be happy to help you
Best regards
Dr. Sagar
Note: For more detailed guidance, please consult an Internal Medicine Specialist, with your latest reports. Click here..
Above answer was peer-reviewed by : Dr. REMY KOSHY
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Answered by
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Dr. Dholariya Sagar Jayantilal

General & Family Physician

Practicing since :2009

Answered : 5898 Questions

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Can The Intake Of Ziprasidone, Olanzapine And Clomipramine Cause Liver Damage?

Brief Answer: Can cause mild hepatic damage Detailed Answer: Hello dear Welcome to HCM and thanks for the query I understand your concern Ziprasidone, Olanzapine, and Clomramine can harm the liver on long time use. But liver damage will not occur in all cases. Chance of liver damage is high if you have already any liver disease. All these drugs can cause mild to moderate elevation of liver enzymes, mild hepatitis. All these side effects are usually mild, asymptomatic and transient, reversing even with continuation of medication. Severe side effects are rare and if occurs it will rapidly disappear after discontinuation of the drugs. You should repeat the liver profile every 6-8 months. So do not worry and take drugs under the advise of your psychiatric. Hope I have answered your query If you have further query then I will be happy to help you Best regards Dr. Sagar