
Constipation With No Bowel Movement, Intense Pain In Mid Abdomen, Later Diarrhea, Normal Colonscopy And Endoscopy Report. Suggestion?

Thank you for the query.
Constipation is usually secondary to the following reasons. I will also let you know how to rule each one of them out with various investigations.
- Mechanical obstruction - At your age and with a normal colonoscopy may be secondary to bands or intusussception / volvulus. It requires a contrast CT (Computed Tomography) with enterography to rule this out.
- Slow transit constipation - Primarily an inherent problem with gut muscles and nerves. It is usually associated with lack of urge for defecation; investigated by motility studies and special stains on biopsy. Hypothyroidism is one of the causes of slow transit constipation. Serum level of Calcium and phosphate say about hyperparathyroidism.
- Idiopathic variant & a diagnosis of exclusion. Hence labelled only after ruling out common and rare causes.
- Constipation variant IBS (Irritable Bowel Syndrome) - The abdominal discomfort rather than the constipation is the predominant symptom. I may agree with your doctor on IBS, has a potential to cause such symptoms. Although I think the investigations have to be thorough before the diagnosis.
Based on the clinical profile I would first suggest a contrast CT abdomen and pelvis with CT enterography along with repeated stool examination as the first line of investigation. Rest can be planned in discussion with your Gastroenterologist.
Regards.

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