Question: Dear Dr.This is reg my mom aged 85.she had a severe MI 8 years back which was resolved by thrombolysis and medication.No further episode for last 8 years. Initially she was prescribed 10 Mg of Korandil twice a day,which has now been brought down to 5 Mg twice a day last 3 years.Constant Echo and ECG being done Last Echo LVF @ 59%.diastolic dysfunction.for First 5 years she was on Korandil 10 mg twice a day..prolomet XL 25 once.,Roseday 5mg once..Clopilet 75 once.and supradyn daily.As per GP s adv only Korandil last 3 years reduced to 5 Mg twice.Now last 3 years along with Prolomet Xl 25 Amlosage 5 s added for better BP control along with others.This was going on smoothly.Last 3 or 4 months BP s eractic and often crosses 150 ..at times n morning pulse touching 90 too.So doc suggested to Add Telma H 40 n morning with break fast, then after lunch prolomet Xl 25 .Amlosafe 5 Mg and n night prolomet Xl 25 along with Clopilet and Roseday,Korandil 5 Mg twice a day.Still by Evening 5 Pm patient s BP not under control and restlessness etc occured.So Amlosafe 5 MG added in night too.With that Things went smoothly.However after 10 days we noticed pedal oedema and body getting weight and some bulge s around lower eyes indicating water retention.So doc.adv us to stop amlosafe totally and prescribed Cilnidipine..Dilnip 10 MG daily only in morning.With Dilnip pedal oedema reduced fully.Again By evening 5 BP touches to 150/ 70 and PATIENT NOT ABLE TO TOLERATE THIS READING AS WE MEASURE AT HOME IN OMRON DEVICE.SHE IS FINE IF READING TOUCHES 120 TO 130/65.Now Doc saying to add DILNIP 10 MG at night too.Last 3 days we are doing the same.But still BP not coming down and patient not comfortable at all.So My question is why cant we go back to Amlosafe 5 Mg only and as and when pedal oedema occurs any diuretic?? PRESENTLY she is taking Morning by BF time Telma H 40.After lunch Dilnip 10 Mg..Korandil 5 mg..prolomet XL 25 Roseday 5 Clopilet 75 supradyn. By Dinner Dilnip 10 mg , Prolonet Xl 25 mg.What is the XXXXXXX dose of Telmisartan also Cilnidipine in a day ?? WHY this fluctuations recently.Things were smooth with amlosafe except for pedeal edema...pedal started when Amlosafe was made twice a day only.For ur info After her attack 8 years back her CT angio detected block in one of the arteries and her Calcium score at dat time was 500 Plus.She s taking daily shelcal500 Mg too.Pl suggest right BP control medicines looking into above details.Also pl clarify does Calcium supplement has any role on reducing the BP medicines efficacy as she is taking Shelcal 500 Mg daily last 3 years after an episode of L4 Comp fracture.Thanx .awaiting for reply.By Evening 5 BP touches 150/70 and pulse 90 ..but morning BF time pulse comes to 70 levels .Kindly Adv on any dosage addition.or reduction..as the problematic time is around 4 to 5 PM as at tht time both BP and pulse shoots up inspite of above so many medicinal combinations.

Doc.Many thanx for ur reply.kly clarify further.
1) what is the XXXXXXX dosage of Telmisartan in a day?? What shd be time gap in case of split dosages?
2)As explained earlier She takes Korandil 5 mg after Lunch as well as Dinner.Originally this was 10 mg twice a day reduced by GP to 5 Mg twice a day.Does Korandil contribute to lowering BP in any way??
3) Does Calcium supplement of 500 MG per day which is going on for last 3 years daily ---Shelcal D contribute or interact with any Calcium channel blocker medicines like Amlodopine or Cilnidipine?? OR any time gap need to be followed between these two type of drugs?
4) Is 5 Mg of Amlodopine equal to 10 Mg of Cilnidipine??
Kly clarify..