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Do High Levels Of CA After Undergoing A Mastectomy Require Further Medical Attention?

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Posted on Mon, 24 Jul 2023
Question: I had a mastectomy in 2014, and have been on both tamoxifen and arimidex for almost 4 years. Attached are two recent reports I have done. Should there be any concern.
doctor
Answered by Dr. Monish De (21 minutes later)
Brief Answer:

CT scan of the whole abdomen

Detailed Answer:

Hi,

Your CA 125 is high and since you had undergone mastectomy and had Tamoxifen and Arimidex I would advise you to do a CT scan of the whole abdomen.

It could be a sign of ovarian cancer and the CT scan will detect any space occupying lesion in your ovary.

If any lesion is found then biopsy has to be done to rule out malignancy

Hope I have answered your query. Let me know if I can assist you further.

Take care

Regards,
Dr Monish De, Oncologist
Above answer was peer-reviewed by : Dr. Yogesh D
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Follow up: Dr. Monish De (33 minutes later)
So the pelvic ultrasound doesn’t give any indication of anything?
doctor
Answered by Dr. Monish De (1 hour later)
Brief Answer:

CT scan detects SOL more accurately than USG

Detailed Answer:

Hi,

Pelvic ultrasound would not detect any space occupying lesion properly.

If any space occupying lesion is found in abdomen then biopsy test has to be done to rule out malignancy and that can be only done with CT scan and not ultrasound.

Hope I have answered your query. Let me know if I can assist you further.

Take care

Regards,
Dr Monish De, Oncologist
Above answer was peer-reviewed by : Dr. Nagamani Ng
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Follow up: Dr. Monish De (23 hours later)
Hi, I have provided some attachments. Please review them.
doctor
Answered by Dr. Monish De (2 hours later)
Brief Answer:

MRI of liver

Detailed Answer:

Hi,

The CT abdomen suggests a mass in your liver.

With a history of breast cancer and elevated Ca 125 I would advise you to go for Magnetic resonance imaging (MRI) of liver

If the mass looks suspicious of malignancy in MRI then biopsy recommended seeing whether cancer has spread to the liver.

Hope I have answered your query. Let me know if I can assist you further.

Take care

Regards,
Dr Monish De, Oncologist

Above answer was peer-reviewed by : Dr. Kampana
doctor
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Follow up: Dr. Monish De (24 minutes later)
Is there any concern about the uterus or that the endometrium is thickened and heterogeneous. Given the CA 125 result and the pelvic ultrasound report, should i be concerned with anything of the uterus? I am post menopause and get heavy periods like every 10 months.
doctor
Answered by Dr. Monish De (38 minutes later)
Brief Answer:

PET scan suggested.

Detailed Answer:

Hi,

Yes as your uterus or that the endometrium is thickened and heterogeneous and Ca 125 is high and you are post menopause and get heavy periods every 10 months you could have an ovary or uterus cancer.

I would advise you to go for a PET scan

Hope I have answered your query. Let me know if I can assist you further.

Take care

Regards,
Dr Monish De, Oncologist
Above answer was peer-reviewed by : Dr. Kampana
doctor
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Follow up: Dr. Monish De (11 days later)
I updated my biopsy report done on 2/23. Any concerns? Also, are the ovaries part of the pelvic organs? The CT Scan did not show anything abnormal with the pelvic organs —- does that include the ovaries, too???
doctor
Answered by Dr. Monish De (6 minutes later)
Brief Answer:

No malignancy present in biopsy report

Detailed Answer:

Hi,

The biopsy report is normal and there is no malignancy present.
CT scan also includes ovaries. Ovaries are also a part of pelvic organs

Hope I have answered your query. Let me know if I can assist you further.

Take care

Regards,
Dr Monish De, Oncologist
Above answer was peer-reviewed by : Dr. Yogesh D
doctor
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Follow up: Dr. Monish De (36 minutes later)
So the ovaries are okay based on the CT scan??
doctor
Answered by Dr. Monish De (10 hours later)
Brief Answer:

PET scan should be done

Detailed Answer:

Hi,

Though your ovaries are normal in CT scan report but your CA 125 is high which is the tumour marker for ovarian cancer.

That is why I would suggest you do a PET scan

Hope I have answered your query.

Take care

Regards,
Dr Monish De, Oncologist
Note: For further queries related to kidney problems Click here.

Above answer was peer-reviewed by : Dr. Kampana
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Dr. Monish De

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Do High Levels Of CA After Undergoing A Mastectomy Require Further Medical Attention?

Brief Answer: CT scan of the whole abdomen Detailed Answer: Hi, Your CA 125 is high and since you had undergone mastectomy and had Tamoxifen and Arimidex I would advise you to do a CT scan of the whole abdomen. It could be a sign of ovarian cancer and the CT scan will detect any space occupying lesion in your ovary. If any lesion is found then biopsy has to be done to rule out malignancy Hope I have answered your query. Let me know if I can assist you further. Take care Regards, Dr Monish De, Oncologist