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Do People With Hemochromatosis Have A Higher Risk Of Contracting HSV2?

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Posted on Sat, 18 Oct 2014
Question: Do people with haemochromotosis have a higher risk of contracting HV2 than normal.
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Answered by Dr. Vjollce Mbiarra (1 hour later)
Brief Answer:
They have higher risk

Detailed Answer:
Hi dear and thanks for your query.

People with haemochromatosis may have higher risk to contract HSV 2 and other viral infection because their immunity may be damaged during their iron overload.

Iron and its binding proteins have immunoregulatory properties, and shifting of immunoregulatory balances by iron excess may produce severe, deleterious physiological effects.
Effects of iron overload include decreased antibody-mediated and mitogen-stimulated phagocytosis by monocytes and macrophages(immmune cells), alterations in T-lymphocyte(immune cells) subsets, and modification of lymphocyte distribution in different compartments of the immune system.

Hope I have explain your question.
All the best

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Above answer was peer-reviewed by : Dr. Shanthi.E
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Answered by
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Dr. Vjollce Mbiarra

OBGYN, Maternal and Fetal Medicine

Practicing since :2006

Answered : 1572 Questions

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Do People With Hemochromatosis Have A Higher Risk Of Contracting HSV2?

Brief Answer: They have higher risk Detailed Answer: Hi dear and thanks for your query. People with haemochromatosis may have higher risk to contract HSV 2 and other viral infection because their immunity may be damaged during their iron overload. Iron and its binding proteins have immunoregulatory properties, and shifting of immunoregulatory balances by iron excess may produce severe, deleterious physiological effects. Effects of iron overload include decreased antibody-mediated and mitogen-stimulated phagocytosis by monocytes and macrophages(immmune cells), alterations in T-lymphocyte(immune cells) subsets, and modification of lymphocyte distribution in different compartments of the immune system. Hope I have explain your question. All the best