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Do Trace Mineral Supplements Interfere With Any Medications? Especially Methotrexate

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Posted on Sat, 6 Jul 2019
Question: Do trace mineral supplements interfere with any medications? Especially Methotrexate, Cimzia, thyroxine, or hypertensive drugs.
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Follow up: Dr. AJEET SINGH (0 minute later)
Do trace mineral supplements interfere with any medications? Especially Methotrexate, Cimzia, thyroxine, or hypertensive drugs.
doctor
Answered by Dr. AJEET SINGH (48 minutes later)
Brief Answer:
Interactions of minerals with drugs.

Detailed Answer:
Hi.
Welcome to "Ask a Doctor" service.
I am Dr Ajeet XXXXXXX

I have gone through your query and here is my opinion.

As per the clinical research,mineral supplements have some important interactions with many drugs commonly used in clinical practice.

Calcium interacts with antibiotics like tetracycline and quinolones like ofloxacin.

Magnesium binds with many drugs and reduce their absorption.

Iron should be avoided with antibiotics,levodopa,digoxin and levothyroxine.

Potassium supplements can increase chances of hyperkalemia with drugs like antihypertensives and some diuretics.

There are no appreciable interactions between mineral supplements and Methotrexate,anti hypertensive medications and cimzia.
Thyroxine and calcium,Iron and PPI drugs have significant interactions.
They should be avoided or doses need to be adjusted.

Because of the likelihood of drug interactions,the mineral supplements should only be ingested when required.
Usually people feel that these supplements are harmless and take them indiscriminately.

Hope that I have answered your query.
If you have any doubts,please let me know.
Regards.
Above answer was peer-reviewed by : Dr. Raju A.T
doctor
doctor
Answered by Dr. AJEET SINGH (0 minute later)
Brief Answer:
Interactions of minerals with drugs.

Detailed Answer:
Hi.
Welcome to "Ask a Doctor" service.
I am Dr Ajeet XXXXXXX

I have gone through your query and here is my opinion.

As per the clinical research,mineral supplements have some important interactions with many drugs commonly used in clinical practice.

Calcium interacts with antibiotics like tetracycline and quinolones like ofloxacin.

Magnesium binds with many drugs and reduce their absorption.

Iron should be avoided with antibiotics,levodopa,digoxin and levothyroxine.

Potassium supplements can increase chances of hyperkalemia with drugs like antihypertensives and some diuretics.

There are no appreciable interactions between mineral supplements and Methotrexate,anti hypertensive medications and cimzia.
Thyroxine and calcium,Iron and PPI drugs have significant interactions.
They should be avoided or doses need to be adjusted.

Because of the likelihood of drug interactions,the mineral supplements should only be ingested when required.
Usually people feel that these supplements are harmless and take them indiscriminately.

Hope that I have answered your query.
If you have any doubts,please let me know.
Regards.
Note: For more detailed guidance, please consult an Internal Medicine Specialist, with your latest reports. Click here..

Above answer was peer-reviewed by : Dr. Raju A.T
doctor
Answered by
Dr.
Dr. AJEET SINGH

General & Family Physician

Practicing since :1994

Answered : 2151 Questions

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Do Trace Mineral Supplements Interfere With Any Medications? Especially Methotrexate

Do trace mineral supplements interfere with any medications? Especially Methotrexate, Cimzia, thyroxine, or hypertensive drugs.