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Do You Think This Could Be The Reason Why My AST And ALT Were Higher Than Two Years Ago?

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Posted on Fri, 4 Apr 2025
Question: Dear doctor - I am quite concerned about some blood test result I got in September.
My AST was 51 and my ALT 130. I'm a 32 year old male, I'm a little bit overweight (178cm, 89kgs) and I do not drink any alcohol. I know that I have a fatty liver but I just wanted to know how serious it is?
I already lost 3 kilos since my last blood test and I work out 3 hours a week. Do you think I have cirrhosis? My blood test from two years ago was ALT 33 and AST 74. I don't know how it got to this stage. I remember I had a burger with fries 14 hours prior to my most recent blood test. Do you think this could be the reason why my AST and ALT were higher than two years ago? I have another blood test in 3 weeks. I'm following a low carb diet and I'm working out a lot so hopefully the numbers would have dropped.
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Answered by Dr. Dr.P.Ratnakar Kini (54 minutes later)
Brief Answer:
Answer given below

Detailed Answer:
Hi,
Thanks for posting your query.
I am Dr.R.K and I am pleased to assist you.
You have significantly high ALT.
The probable cause is fatty liver. I presume you have ruled out other causes like hepatitis B and C infection and other metabolic liver diseases.
You probably have non alcoholic steato hepatitis.
The risk factor is obesity. Your BMI is 28.1 which is high. It has to be under 25.
You need to reduce weight and bring the BMI to below 25.
You most likely are not having cirrhosis as the scan did not show any features of cirrhosis. If the scan was not done recently, you can get it done again.
Also if you upload the complete report of liver function, I can have a look at it and tell whether you have cirrhosis.
Even if there is no cirrhosis, I would advise you to undergo fibroscan to look for fibrosis.
You can consult your gastroenterologist for prescription of Obeticholic acid/Saroglitazar for the treatment of non alcoholic steato hepatitis. As said above you need to reduce weight also.
Regards,
Dr.R.K.
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Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
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Answered by
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Dr. Dr.P.Ratnakar Kini

Gastroenterologist

Practicing since :1994

Answered : 2203 Questions

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Do You Think This Could Be The Reason Why My AST And ALT Were Higher Than Two Years Ago?

Brief Answer: Answer given below Detailed Answer: Hi, Thanks for posting your query. I am Dr.R.K and I am pleased to assist you. You have significantly high ALT. The probable cause is fatty liver. I presume you have ruled out other causes like hepatitis B and C infection and other metabolic liver diseases. You probably have non alcoholic steato hepatitis. The risk factor is obesity. Your BMI is 28.1 which is high. It has to be under 25. You need to reduce weight and bring the BMI to below 25. You most likely are not having cirrhosis as the scan did not show any features of cirrhosis. If the scan was not done recently, you can get it done again. Also if you upload the complete report of liver function, I can have a look at it and tell whether you have cirrhosis. Even if there is no cirrhosis, I would advise you to undergo fibroscan to look for fibrosis. You can consult your gastroenterologist for prescription of Obeticholic acid/Saroglitazar for the treatment of non alcoholic steato hepatitis. As said above you need to reduce weight also. Regards, Dr.R.K.