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Does Cephalexin Interact With Ranitidine?

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Posted on Wed, 16 Nov 2016
Question: Is it safe to take cephalexin 500mg and Ranitidine 150mg at the same time and no side effects from the medicine
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Answered by Dr. Vaishalee Punj (2 hours later)
Brief Answer:
They may have individual side effects

Detailed Answer:
Hi
Thanks for posting your query on HealthcareMagic.

Regarding drug interaction between ranitidine and cephalexin, there is no significant interaction. Ranitidine reduces gastric acidity and may result in bioavailability of some cephalosporins that need gastric acid to covert from prodrug to active drug. Their bioavailability may decrease. But bioavailability of this cephalosporin (cephalexin) is shown to be unaffected.

They may have individual side effects of their own but if taken together should not cause any specific side effect.

Ranitidine is recommended to be taken atleast half hour before meals. Cephalexin can be taken with or without meals but is taken with meals to reduce gastric discomfort.

Are you experiencing any side effects? Do let me know.

Regards
Dr Vaishalee
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Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
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Answered by
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Dr. Vaishalee Punj

General & Family Physician

Practicing since :2003

Answered : 3270 Questions

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Does Cephalexin Interact With Ranitidine?

Brief Answer: They may have individual side effects Detailed Answer: Hi Thanks for posting your query on HealthcareMagic. Regarding drug interaction between ranitidine and cephalexin, there is no significant interaction. Ranitidine reduces gastric acidity and may result in bioavailability of some cephalosporins that need gastric acid to covert from prodrug to active drug. Their bioavailability may decrease. But bioavailability of this cephalosporin (cephalexin) is shown to be unaffected. They may have individual side effects of their own but if taken together should not cause any specific side effect. Ranitidine is recommended to be taken atleast half hour before meals. Cephalexin can be taken with or without meals but is taken with meals to reduce gastric discomfort. Are you experiencing any side effects? Do let me know. Regards Dr Vaishalee