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Does Duloxetine Interact With Naproxen?

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Posted on Mon, 15 May 2017
Question: Does Duloxetine interact poorly with naproxen?
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Answered by Dr. Panagiotis Zografakis (58 minutes later)
Brief Answer:
there are interactions

Detailed Answer:
Hello,

using naproxen with duloxetine is not recommended because duloxetine may potentiate the ulcerogenic effects of naproxen and cause peptic ulcer and bleeding. If you need a stronger analgesic then you can continue using naproxen and add paracetamol (acetminophen) and/or a mild opioid (low dose opioid).

I hope it helps!
Kind Regards!
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Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
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Answered by
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Dr. Panagiotis Zografakis

Internal Medicine Specialist

Practicing since :1999

Answered : 3815 Questions

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Does Duloxetine Interact With Naproxen?

Brief Answer: there are interactions Detailed Answer: Hello, using naproxen with duloxetine is not recommended because duloxetine may potentiate the ulcerogenic effects of naproxen and cause peptic ulcer and bleeding. If you need a stronger analgesic then you can continue using naproxen and add paracetamol (acetminophen) and/or a mild opioid (low dose opioid). I hope it helps! Kind Regards!