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Does Hydrocodone Interact With Seroquel?

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Posted on Fri, 7 Oct 2016
Question: Recently I took 10 mg hydrocodone and 400 mills of Seroquel. I had a severe reaction, was taken to the hospital via 911, and at the hospital they XXXXXXX I was abusing Hydrocodone, gave me Narcan sp, and a long tirade about how I was probably a junkie. The Seroquel made it hard to talk.
doctor
Answered by Dr. Dr. Ashok Kumar Choudhary (59 minutes later)
Brief Answer:
I don't understand rational for 400 mg seroquel in single day

Detailed Answer:
Hello,
Thanks for using Healthcaremagic.

I read your query and understand your concerns.

First of all I do not think anybody can start with 400 mg of seroquel from the day One. The medication is used for variety of reasons and often we start with 25-50 mg per day and increase it to target dose slowly.

The use of Narcan SP indicates that you had sign of Opioid toxicity which are not possible with seroquel.
No healthcare facility will use narcan SP for reaction caused by seroquel.

I am sorry but the query have some missing points. Can you please clarify ?
Thanks and regards.
Above answer was peer-reviewed by : Dr. Arnab Banerjee
doctor
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Follow up: Dr. Dr. Ashok Kumar Choudhary (1 hour later)
The Seroquel has been prescribed for sleep. I am on the bi-polar spectrum. We stated out at 100 msg went to 200 and in this last year, 400. That, however is the red herring. I just wanted to know if the Seoquel exacerbated the 10 msg of Hydrocodone. Also, 10 msg is a high dose but tolerated well usually. What made these people in the hospital think I was steeped in opiates when I was not?
doctor
Answered by Dr. Dr. Ashok Kumar Choudhary (51 minutes later)
Brief Answer:
No such excerabation known in literature

Detailed Answer:
Hello,
Thanks for reverting back to me.

I never seen any patient presenting with such symptoms with use of seroquel and hydrocodone.

It is possible that unknowingly you took more than prescribed dose leading to toxic symptoms. It is possible as seroquel causes severe sedation.

I hope this helps you.
If you have more questions feel free to write back to me.
Thanks and regards.
Note: For further guidance on mental health, Click here.

Above answer was peer-reviewed by : Dr. Nagamani Ng
doctor
Answered by
Dr.
Dr. Dr. Ashok Kumar Choudhary

Psychiatrist

Practicing since :2000

Answered : 3350 Questions

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Does Hydrocodone Interact With Seroquel?

Brief Answer: I don't understand rational for 400 mg seroquel in single day Detailed Answer: Hello, Thanks for using Healthcaremagic. I read your query and understand your concerns. First of all I do not think anybody can start with 400 mg of seroquel from the day One. The medication is used for variety of reasons and often we start with 25-50 mg per day and increase it to target dose slowly. The use of Narcan SP indicates that you had sign of Opioid toxicity which are not possible with seroquel. No healthcare facility will use narcan SP for reaction caused by seroquel. I am sorry but the query have some missing points. Can you please clarify ? Thanks and regards.