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Does Losartan With Metoprolol Or Micardis With Metoprolol Have Lesser Side Effects?

Posted on Mon, 20 Jul 2015

Question: Please Which combination is better. Losartan Potassium and Metropolol or Mircadis and Metropolol

Answered by Dr. Noble Zachariah (22 minutes later)

Brief Answer:
Both are similar

Detailed Answer:
Hello,

Welcome and thanks for your query.
Both Losartan and Micardis ( telmosartan) are ARBs and the benefits and side effects are similar.
Metoprolol and Losartan have similar half lives and so if available as a combination pill, this combination would be better than with Micardis which has a longer half life than Metoprolol.
If the medicines are to be used separately, I would prefer Metoprolol and Micardis as Micardis can be taken once a day and Metoprolol twice a day for optimum effect. So with Micardis you can take one tablet less.

Best wishes,

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar

Follow up: Dr. Noble Zachariah (2 hours later)

If you are taking Metropolol and Micardis separately, can you substitute Losartan Potassium for Mircardis if you run out of Micardis

Secondly what is the difference between Losartan and Losartan Potassium

Answered by Dr. Noble Zachariah (1 hour later)

Brief Answer:
Yes

Detailed Answer:
Losartan can be substituted for Micardis. You should adjust the dose according to the blood pressure.
Losartan is available as Losartan Potassium. The active ingredient Losartan is marketed as its Potassium salt

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar

Follow up: Dr. Noble Zachariah (18 minutes later)

So if losartan potassium can be substituted for micardis can they be used interchangeably if needed

Answered by Dr. Noble Zachariah (1 hour later)

Brief Answer:
yes

Detailed Answer:
They are both ARBs and have similar benefits and side effects. The may be used in place of each other.
As their half lives are different, you should check your BP and adjust dose if required.

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar

Follow up: Dr. Noble Zachariah (6 hours later)

25mg losartan potassium or 40mg micardis which one is likely to cause more side effects

Secondly which one is more likely to cause erectile dysfunction

Thirdly examples of some of the blood pressure medication that does not cause erectile dysfunction

Answered by Dr. Noble Zachariah (9 hours later)

Brief Answer:
Statistically no significant difference.

Detailed Answer:
ED is due to a number of causes of which psychological factors are the commonest. Hypertension itself is a cause.
Of the antihypertensives, ARBs probably cause the least. There was a study published some years ago, in which ARB showed benefits.
In studies comparing efficacy and side effects Losartan 50mg is compared with 40mg of Micardis. There's no statistically significant difference between the two.

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar

Follow up: Dr. Noble Zachariah (1 hour later)

Thank you for your answers

Answered by Dr. Noble Zachariah (1 minute later)

Brief Answer:
Welcome

Detailed Answer:
It was nice interacting with you.
Do feel free to contact me if you have more queries.
Wish you good health

Note: For further queries related to coronary artery disease and prevention, click here.

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar