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Does Methadone Interact With Any Other Drug?

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Posted on Tue, 12 Apr 2016
Question: Which of my medications are in conflict.
ClonzaePAM, torsemide, methadone, aspirin, aleve, kl or-con,flustaton, trazadone,omeprazole, flustatin metropol, ropinirole, thyroxine, levothyrozine, pro vigil-as needed. I am being treated for arthritis, high cholesterol, fibromyalgia, osteoporosis, do to hospital/Doctor mistake they missed a hole in my lung. They sent me home with a repaired broken ankle due to a car accident. Seven hours later the called me and told me to rush back to the hospital. The pnmothorax was picked up by a second radiologist. The doctors had forgotten to check the possible effects of the air bag. In the seven hours I had picked up a serious staph infection. I was given a super strong antibiotic. This particular drug produced a serious complication. It started to destroy my tendons. My tendons are still in trouble. For example I have no Achilles' tendons. In a later operation for a cyst the doctor discovered that some of my internal organs are not quite where they should be. During this 10 to 15 year ordeal except for the last one each Doctor I saw denied any knowledge of what caused my myriad of problems. Many of the causes that were discovered by me, my strong knowledge of biology and my trusty I-pad. I was in the hospital for 2 weeks. it was crittondon hospital in XXXXXXX hills Michigan. Other mistakes there could have killed me. Just as an example my chest tube hurt like hell for 3 days. I couldn't see what was wrong but blood coming out from the chest tube did not look good. During those 3 days I was constantly pushing the nurse call button. I finally called the hospital phone number, told her of my problem. The problem was that the call light was not working. I could further bore you with horror stories but this is not a propitious time to time to go into it.


XXXXXXX XXXX
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doctor
Answered by Dr. Deepak (19 hours later)
Brief Answer:
Major interaction is between METHADONE & TRAZADONE

Detailed Answer:
Hi....
I have read your description and understand your concern.
I can understand better because my grandfather is also on 5 -6 different tablets daily.
I have found one major and some moderate interactions with the drugs you are currently taking. Major interaction is between Methadone and Trazadone. Rarely this might cause irregular heart beats which may be life threatening. The chances will increase if you have any heart conditions.
Some other moderate interactions are as follows
Aleve & Metoprolol, Trazodone & Ropinirole, Trazodone & Torsemide, Omeprazole & Torsemide, Aleve & aspirin.
I would request you to kindly go back to your doctor and get ONLY NECESSARY DRUGS from your list of drugs.
Hope I have answered your query. Let me know if I can assist you further.

Above answer was peer-reviewed by : Dr. Yogesh D
doctor
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Follow up: Dr. Deepak (8 hours later)
I take methadone because it is the ONLY drug my doctor's have found that will take away the horrible pain from fibromyalgia. I three 3 tabs per day 10 mg? tabs. It keeps the pain away until about 2:30 P.M. I have figured out that the pain starts in my piriformis muscles under the gluts. I figured it out it our when one doc had me do exercises and when he had me do the piriformis stretch I nearly hit the ceiling. From there it spreads throughout my body and gets to the point where even touching my shins is horribly painful. I am given the trazadone so that I can sleep at night. That is the only drug that allows me to sleep. I have been following this regimen of drugs for 15 years. Aleve is the only drug that even touches the arthritic pain. Another interesting fact is that the fibro first hit me in a fairly mild way when I started puberty and it really blew up at menopause. Any reason why these two events would be connected? I only go to MDS although some docs have put me through things that range from acupuncture to hypnosis and everything in between. Thank-you so much for your help so far. The doctors I have now are excellent but baffled.
XXXXXX XXXXX



As above
doctor
Answered by Dr. Deepak (6 hours later)
Brief Answer:
yes they are well connected as per research

Detailed Answer:
Hi..
Thank you for your patience.
As I found few research documents mentioning positive relationship between fibromyalgia (FM) and menopause. It says that fibromyalgia symptoms are more severe in post-menopausal (PM)women than in women who are still menstruating. Typically PM women produce 40% lesser estrogen than a menstruating women. It may be related to the level of estrogen circulating in the body.
It is these hormonal changes of menopause can cause crankiness and soreness. It may be increased by sleeplessness, which is one of the main features of fibromyalgia. Loss of calcium and other minerals in menopause also leads to body aches. I remember some of the physicians giving Estrogen replacement to their patients with good clinical outcome. You may want to discuss this with your doctor if this hormone does not interfere with other essential drugs that you take.

Hope I have answered your query.Please use any answer clarification before closing and rating this answer. I will be happy to explain or expand on any issues you might have.
Have a great day. Take care.
Note: For more detailed guidance, please consult an Internal Medicine Specialist, with your latest reports. Click here..

Above answer was peer-reviewed by : Dr. Deepak
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Answered by
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Dr. Deepak

General & Family Physician

Practicing since :2012

Answered : 149 Questions

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Does Methadone Interact With Any Other Drug?

Brief Answer: Major interaction is between METHADONE & TRAZADONE Detailed Answer: Hi.... I have read your description and understand your concern. I can understand better because my grandfather is also on 5 -6 different tablets daily. I have found one major and some moderate interactions with the drugs you are currently taking. Major interaction is between Methadone and Trazadone. Rarely this might cause irregular heart beats which may be life threatening. The chances will increase if you have any heart conditions. Some other moderate interactions are as follows Aleve & Metoprolol, Trazodone & Ropinirole, Trazodone & Torsemide, Omeprazole & Torsemide, Aleve & aspirin. I would request you to kindly go back to your doctor and get ONLY NECESSARY DRUGS from your list of drugs. Hope I have answered your query. Let me know if I can assist you further.