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Does St.John's Wort Interfere With Avapro And Lipitor?

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Posted on Fri, 27 Mar 2015
Question: Can you please tell me how St. John's wort interferes with my necessary drugs such as avapro, Lipitor, placid
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Answered by Dr. Chintan Solanki (1 hour later)
Brief Answer:
Yes St. John's wort can interfer with your necessary durgs

Detailed Answer:
Hello,

Thanks for writing to us.

St. John's wort is a plant Hypericum perforatum. This herb is often used as an antidepressant. But due to its chemical composition( arachidonate 5-lipoxygenase inhibitor and COX-1 inhibitor) it causes many drug drug interaction.It can decrease efficacy of lipitor and your cholesterlol level may be increased. It can reduce effectiveness of placid also.

And for your information St. John's wort is not approved therapy for depression by FDA.

If I were your treating doctor/psychiatrist I would not prefer St. John's wort at all.

Hope I have answered your query, I will be happy to help further.

Regards,
Dr.Chintan Solanki.
Note: For more detailed guidance, please consult an Internal Medicine Specialist, with your latest reports. Click here..
Above answer was peer-reviewed by : Dr. Shanthi.E
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Answered by
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Dr. Chintan Solanki

Psychiatrist

Practicing since :2007

Answered : 2406 Questions

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Does St.John's Wort Interfere With Avapro And Lipitor?

Brief Answer: Yes St. John's wort can interfer with your necessary durgs Detailed Answer: Hello, Thanks for writing to us. St. John's wort is a plant Hypericum perforatum. This herb is often used as an antidepressant. But due to its chemical composition( arachidonate 5-lipoxygenase inhibitor and COX-1 inhibitor) it causes many drug drug interaction.It can decrease efficacy of lipitor and your cholesterlol level may be increased. It can reduce effectiveness of placid also. And for your information St. John's wort is not approved therapy for depression by FDA. If I were your treating doctor/psychiatrist I would not prefer St. John's wort at all. Hope I have answered your query, I will be happy to help further. Regards, Dr.Chintan Solanki.