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Does Trifluoperazine Interact With Procyclidine?
Question: Dear doctor - wanted to check with you about trifuoperazine and procyclodine combination. Does procyclodine prevent the eps caused by trifuoperazine? How much of procyclodine is required to counter eps, I am taking 3 mg of trifuoperazine in the morning and 1 mg in the night, how much of procyclodine should I take? Is 2.5 mg (1/2 in the morning and 1/2 in the afternoon) is ok to control eps or it should be increased, if yes, how much should I increase it by?
Brief Answer:
Procyclidine is also an anticholinergic drug
Detailed Answer:
Hello again,
I hope you are doing good.
Procyclidine is also an anticholinergic like Trihexyphenidyl.
Yes Procyclidine also prevents EPS caused by Trifluperazine.
The doses are about 2.5-5 mg twice a day. (I have never used this drug in my patients, I am saying this on the basis of books only).
Yes 2.5 mg per day will be sufficient with 4 mg Trifluperazine per day.
No need to increase the doses.
Thanks and Take care
Procyclidine is also an anticholinergic drug
Detailed Answer:
Hello again,
I hope you are doing good.
Procyclidine is also an anticholinergic like Trihexyphenidyl.
Yes Procyclidine also prevents EPS caused by Trifluperazine.
The doses are about 2.5-5 mg twice a day. (I have never used this drug in my patients, I am saying this on the basis of books only).
Yes 2.5 mg per day will be sufficient with 4 mg Trifluperazine per day.
No need to increase the doses.
Thanks and Take care
Above answer was peer-reviewed by :
Dr. Chakravarthy Mazumdar
Good evening doctor - I was taking stelabid 2 mg (isopropramide 5 mg+ trifuoperazine 2 mg) in the morning. my doctor made it 3 mg ( 2mg stelabid + 1 mg trifuoperazine) in the morning and 1 mg trifuoperazine in the night along with 2mg tremadin in the morning. Since the time i have started this combination, i have following symptoms:
very dry lips and a strange feeling on the lips with a slight bitter taste in the mouth. I have following questions:
is it happening because of tremadin or increased dose of trifuoperazine causing this?
will exchanging tramadine to kemadrin help?
do you think taking 3 mg stelabid in the morning and 1 mg stelabid in the night will help rather than taking pure trifluoperazine?
Between pacitane, kemadrine and tremadin, which one has lesser side effects?
my doctor says i should try baxol as it has lesser side effects,is it true?
very dry lips and a strange feeling on the lips with a slight bitter taste in the mouth. I have following questions:
is it happening because of tremadin or increased dose of trifuoperazine causing this?
will exchanging tramadine to kemadrin help?
do you think taking 3 mg stelabid in the morning and 1 mg stelabid in the night will help rather than taking pure trifluoperazine?
Between pacitane, kemadrine and tremadin, which one has lesser side effects?
my doctor says i should try baxol as it has lesser side effects,is it true?
Brief Answer:
Baxol can be tried.
Detailed Answer:
Hello again
Your doses have been increased and you are on 5 mg Isopropamide, 2 mg Tremadin and 4 mg Trifluperazeine. Both Isopropamide and Tremadin are anticholinergic drugs and this is the reason you are having anticholinergic side effects like dry lips, altered taste sensation etc.
In my opinion either Stelabid plain should be used or plain Trifluperazine with some anticholinergic drug like Pacitane.
Pacitane is commonly used and is better tolerated compared to others.
Baxol is also good and has less side effects and tolerated even better than Pacitane.
Thanks.
Baxol can be tried.
Detailed Answer:
Hello again
Your doses have been increased and you are on 5 mg Isopropamide, 2 mg Tremadin and 4 mg Trifluperazeine. Both Isopropamide and Tremadin are anticholinergic drugs and this is the reason you are having anticholinergic side effects like dry lips, altered taste sensation etc.
In my opinion either Stelabid plain should be used or plain Trifluperazine with some anticholinergic drug like Pacitane.
Pacitane is commonly used and is better tolerated compared to others.
Baxol is also good and has less side effects and tolerated even better than Pacitane.
Thanks.
Above answer was peer-reviewed by :
Dr. Chakravarthy Mazumdar
I am taking kemadrin 2.5 mg in the morning and 1.25 in the afternoon…it is helping me with anxiety too ( thats what i feel after taking it). Was wanting to check if i can increase the dosage of it in the morning. is it okay to take more than 2.5 mg if yes how should i increase its dosage? what is the prescribed dosage for it?
Brief Answer:
Yes you can increase the doses
Detailed Answer:
Hello again
Yes you can increase the dose in morning and its ok to take more Thant 2.5 mg. You can add 1.25 mg in morning in addition to 2.5 mg dose.
I haven't used this specific drug to my patients of anxiety and I am not aware of its use in anxiety. But yes it can be used even 2.5 mg three times a day for drug induced restlessness and akathisia.
Thanks
Yes you can increase the doses
Detailed Answer:
Hello again
Yes you can increase the dose in morning and its ok to take more Thant 2.5 mg. You can add 1.25 mg in morning in addition to 2.5 mg dose.
I haven't used this specific drug to my patients of anxiety and I am not aware of its use in anxiety. But yes it can be used even 2.5 mg three times a day for drug induced restlessness and akathisia.
Thanks
Above answer was peer-reviewed by :
Dr. Chakravarthy Mazumdar
Good evening doctor - i am taking kemadrin 2.5 mg in the morning and 1.25 in the afternoon along with stelabid 2mg + trifluoperazine 1 mg in the morning and satlabid 1 mg in the night. I have following questions:
i am getting indigestion and acidity along with GERD, is it because of kemadrin or trifluoperazine?
if it is because of kemadrin, can i stop it? since my doctor has given me this to control eps because of trifluoperazine, will stopping it cause eps?
Since stelabid has two molecules (trifluoperazine + isopromide), the chances of it causing eps are same as trifluoperazine or it causes lesser eps since it has two molecules?
Was reading on the net that trifluoperazine can cause permanent eps, is it dose related? the dose i am taking is ok without kemadrin or at that dose also it can cause eps?
what is the dose of stelabid that can be taken without any fear of eps?
Also are the eps coz of trifluoperazine gender and age related? which gender is more prone to eps and what age group?
pls advise.
i am getting indigestion and acidity along with GERD, is it because of kemadrin or trifluoperazine?
if it is because of kemadrin, can i stop it? since my doctor has given me this to control eps because of trifluoperazine, will stopping it cause eps?
Since stelabid has two molecules (trifluoperazine + isopromide), the chances of it causing eps are same as trifluoperazine or it causes lesser eps since it has two molecules?
Was reading on the net that trifluoperazine can cause permanent eps, is it dose related? the dose i am taking is ok without kemadrin or at that dose also it can cause eps?
what is the dose of stelabid that can be taken without any fear of eps?
Also are the eps coz of trifluoperazine gender and age related? which gender is more prone to eps and what age group?
pls advise.
Brief Answer:
You can stop Kemadrin.
Detailed Answer:
Hello again
1) Kemadrin is an anticholinergic drug and this could cause nausea, vomiting, GIT upset etc side effects. This could be the cause of indigestion.
2) Since you are taking Slelabid (Trifluperazeine and Isopropamide) 3 mg and Trifluperazine plain 1 mg a day. Isopropamide is also an anticholinergic drug. So I don't think stopping Kemadrin would cause or increase risk of EPS. Isopropamide should control these, but yes individual to individual variations can be seen.
3) No the risk is lower than plain Trifluperazine.
4) Yes the long term use of drug with high dose could increase risk of Tardive dyskinesia. You are not on high dose. A lot of patients come in my OPD and are taking Trifluperazine since long but they are doing good.
5) Try not to increase dose of Stelabid more than 4 mg per day.
6) Yes the EPS are age and gender related. Akathisia are seen more commonly in females while dystonias more in young males. But there is no clear cut difference. Elderly patients are more prone to develop permanent EPS.
Thanks.
You can stop Kemadrin.
Detailed Answer:
Hello again
1) Kemadrin is an anticholinergic drug and this could cause nausea, vomiting, GIT upset etc side effects. This could be the cause of indigestion.
2) Since you are taking Slelabid (Trifluperazeine and Isopropamide) 3 mg and Trifluperazine plain 1 mg a day. Isopropamide is also an anticholinergic drug. So I don't think stopping Kemadrin would cause or increase risk of EPS. Isopropamide should control these, but yes individual to individual variations can be seen.
3) No the risk is lower than plain Trifluperazine.
4) Yes the long term use of drug with high dose could increase risk of Tardive dyskinesia. You are not on high dose. A lot of patients come in my OPD and are taking Trifluperazine since long but they are doing good.
5) Try not to increase dose of Stelabid more than 4 mg per day.
6) Yes the EPS are age and gender related. Akathisia are seen more commonly in females while dystonias more in young males. But there is no clear cut difference. Elderly patients are more prone to develop permanent EPS.
Thanks.
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Above answer was peer-reviewed by :
Dr. Prasad
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