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Does Intake Of Topamax Help In Treating Bipolar Disorder?

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Posted on Fri, 1 Jul 2016
Question: I already take depakote for my bipolar disorder and now my dr. wants to put me on Topamax in addition to my primidone and gabapentin that i take for tremors. She says the topamax will help with bipolar and tremors but when I looked online it looked like they may not be right to use together. I am confused.
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Answered by Dr. Dr. Ashok Kumar Choudhary (9 minutes later)
Brief Answer:
They can be used together

Detailed Answer:
Hello,
Thanks for using Healthcaremagic.

I see the two reasons for use of Topamax in addition to current medication but I feel primidone should be removed.

The first reason is obviously bipolar diorder as Topamax is also a mod stabilizer and researched well for use in bipolar disorder. Although the data are not robust but I feel when you have another indication for it, it is a worth try.

The second is Migraine. Topamax is highly effective in resistant migraine and that could be another reason for its use.

In addition I feel since Primidone is enzyme inducer it will affect the ability of other medications so removing it from treatment regimen should be considered if possible.

I hope this helps you.
Thanks and regards.
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Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
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Answered by
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Dr. Dr. Ashok Kumar Choudhary

Psychiatrist

Practicing since :2000

Answered : 3347 Questions

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Does Intake Of Topamax Help In Treating Bipolar Disorder?

Brief Answer: They can be used together Detailed Answer: Hello, Thanks for using Healthcaremagic. I see the two reasons for use of Topamax in addition to current medication but I feel primidone should be removed. The first reason is obviously bipolar diorder as Topamax is also a mod stabilizer and researched well for use in bipolar disorder. Although the data are not robust but I feel when you have another indication for it, it is a worth try. The second is Migraine. Topamax is highly effective in resistant migraine and that could be another reason for its use. In addition I feel since Primidone is enzyme inducer it will affect the ability of other medications so removing it from treatment regimen should be considered if possible. I hope this helps you. Thanks and regards.