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Does Requirement Of Insulin Reduce Greatly In Kidney Failure Patients?
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Detailed answer...
Hello,
Thanks for the query.
I have read your query and understand your point.
There is nothing unusual in kidney failure patients to need less amount of insulin doses and in some cases, no need for any injectable insulin.
You see insulin is cleared by kidneys during it's metabolism in body.
Once the kidney is damaged,the amount of insulin cleared by kidneys get diminished tremendously, resulting in high levels of circulating insulin in body and consequently low requirement of injection insulin.
In some cases a person can do well even without use of injection insulin because in those cases,the amount of endogenous insulin ( natural insulin produced by your pancreas ) produced is sufficient to take care of blood sugar levels. This is what is happening with your mother.
Her sugar levels are controlled well due to the insulin produced by her body and hence no need to take any external injection insulin.
Such type of patients are well cared in a hospital set up because of regular and constant monitoring.
I hope it helps,however you are most welcome to revert to me for any further query.
Best of luck
Thanks
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Insulin resistance responsible for high requirement of insuin
Detailed answer:
Hello,
I think you have not understood what I wrote.
You see the clearance of insulin by way of filtration through kidneys is grossly affected because kidneys have been damaged completely. With the result there is lot of insulin circulating in the body (endogenously produced by pancreas ).
This amount of circulating insulin is enough to take care of blood sugar levels.
More over weightloss also results in lesser amount of insulin requirement.
Another reason is that dialysis improves insulin resistance which is hall mark of type 2 diabetes.
This insulin resistance was primarily responsible for high requirement of insulin before the advent of kidney failure.
Once the blood sugar levels are properly controlled,then there is no reason for HYPERGLYCEMIA effects.
Thanks
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Many Thanks for your answer.
Longstanding uncontrolled diabetes results in various complications like kidney failure and heart failure which in turn is now responsible for continuous deterioration of her condition.
Longstanding diabetes is responsible for various types of micro as well as macro vascular complications in the body.
Thanks
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